TCM-ID Component

Description of the Component

Component ID	TCMH212
Latin Name	Iphigenia indica
English Name	Indian iphigenia
Chinese Pinyin Name	Cao Bei Mu
中文名	è‰è´æ¯
TCM Properties	Warm,Bitter
TCM Meridians	Lung,Spleen,Stomach,Liver
Therapeutic Class English	For desolving phlegm, stopping cougth, and soothing breathing
Therapeutic Class Chinese	åŒ–ç—°æ¢å’³å¹³å–˜
Functions	For desolving phlegm
Toxicity	Extremely Toxic
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Classical Prescriptions
Barcode ID	GBVY1310-14, GBVC2253-11
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2425	Lump Desolving Fries	å°è¥ç…Ž
TCMF2468	Lung Clearing Decoction
TCMF2347	Tumor Desovling Decoction

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT1	EHMT2	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3	Transferase	Q96KQ7
TCMT125	GBA	Beta-glucocerebrosidase	Hydrolase	P04062
TCMT150	RORC	Nuclear receptor ROR-gamma	Nuclear receptor	P51449
TCMT176	SOAT1	Acyl coenzyme A:cholesterol acyltransferase 1	Transferase	P35610
TCMT213	SLC22A1	Solute carrier family 22 member 1	Transporter	O15245
TCMT217	CYP2C8	Cytochrome P450 2C8	Oxidoreductase	P10632
TCMT219	CYP1A2	Cytochrome P450 1A2	Oxidoreductase	P05177
TCMT248	CXCL8	Interleukin-8	Unclassified	P10145
TCMT276	SLCO2B1	Solute carrier organic anion transporter family member 2B1	Transporter	O94956
TCMT277	SLCO1B3	Solute carrier organic anion transporter family member 1B3	Transporter	Q9NPD5
TCMT278	SLCO1B1	Solute carrier organic anion transporter family member 1B1	Transporter	Q9Y6L6
TCMT31	CYP2C19	Cytochrome P450 2C19	Oxidoreductase	P33261
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT34	CYP2D6	Cytochrome P450 2D6	Oxidoreductase	P10635
TCMT42	KMT2A	Histone-lysine N-methyltransferase MLL	Transferase	Q03164
TCMT556	HDAC2	Histone deacetylase 2	Hydrolase	Q92769
TCMT557	HDAC1	Histone deacetylase 1	Hydrolase	Q13547
TCMT690	HDAC3	Histone deacetylase 3	Hydrolase	O15379
TCMT87	CYP2C9	Cytochrome P450 2C9	Oxidoreductase	P11712

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1136	Neuraminidase
TCMT1172	Staphylococcus aureus subsp. aureus RN4220
TCMT1179	Escherichia coli ATCC 8739
TCMT1218	Staphylococcus aureus
TCMT1251	Candida albicans
TCMT1255	Human immunodeficiency virus 1
TCMT1286	Bacillus cereus
TCMT1438	Plasmodium falciparum
TCMT1458	Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC931
Formula: C22H25NO6

Common Name	Colchicine
IUPAC Name	N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Canonical SMILES	COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)N=C(O)C)OC
Standard InCHI	InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1
Standard InCHIKey	IAKHMKGGTNLKSZ-INIZCTEOSA-N
External Identifiers	ChEMBL [CHEMBL107]; PubChem [6167];
Reference of Component-Ingredient Pair	28389280

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1260	Veratrum nigrum	Li Lu	è—œèŠ¦
TCMH212	Iphigenia indica	Cao Bei Mu	è‰è´æ¯

Ingredient ID: TCMC2517
Formula: C14H10O4

Common Name	2-Hydroxy-1-Methoxyxanthone
IUPAC Name	2-hydroxy-1-methoxyxanthen-9-one
Canonical SMILES	COc1c(O)ccc2c1c(=O)c1c(o2)cccc1
Standard InCHI	InChI=1S/C14H10O4/c1-17-14-9(15)6-7-11-12(14)13(16)8-4-2-3-5-10(8)18-11/h2-7,15H,1H3
Standard InCHIKey	ATPZBKJDXXSOFC-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1923834]; PubChem [10399460];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH212	Iphigenia indica	Cao Bei Mu	è‰è´æ¯

Ingredient ID: TCMC2264
Formula: C13H8O4

Common Name	1,7-Dihydroxyxanthone
IUPAC Name	1,7-dihydroxyxanthen-9-one
Canonical SMILES	Oc1ccc2c(c1)c(=O)c1c(o2)cccc1O
Standard InCHI	InChI=1S/C13H8O4/c14-7-4-5-10-8(6-7)13(16)12-9(15)2-1-3-11(12)17-10/h1-6,14-15H
Standard InCHIKey	KDXFPEKLLFWHMN-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL389166]; PubChem [5281631];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1448	Mangifera indica	Mang Guo Ye	èŠ’æžœå¶
TCMH1880	Moschus moschiferus	She Xiang	éºé¦™
TCMH212	Iphigenia indica	Cao Bei Mu	è‰è´æ¯
TCMH1462	Moschus moschiferus	Mao She Xiang	æ¯›éºé¦™
TCMH1463	Moschus moschiferus	Mao She Xiang Jin Gao	æ¯›éºé¦™æµ¸è†
TCMH1717	Moschus moschiferus	Ren Gong She Xiang	äººå·¥éºé¦™
TCMH2201	Securidaca inappendiculata	Wu Wei Teng	äº”å‘³è—¤
TCMH2556	Polygala tenuifolia	Yuan Zhi Liu Jin Gao	è¿œå¿—æµæµ¸è†
TCMH2554	Polygala tenuifolia	Yuan Zhi	è¿œå¿—
TCMH2555	Polygala tenuifolia	Yuan Zhi Jin Gao	è¿œå¿—æµ¸è†

Ingredient ID: TCMC1612
Formula: C22H25NO6

Common Name	N-(1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl)Acetamide
IUPAC Name	N-(1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl)acetamide
Canonical SMILES	COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1C(CC2)N=C(O)C)OC
Standard InCHI	InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
Standard InCHIKey	IAKHMKGGTNLKSZ-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL87]; PubChem [2833];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1813	Asarum sagittarioides	Shan Ci Gu	å±±æ…ˆè‡
TCMH1260	Veratrum nigrum	Li Lu	è—œèŠ¦
TCMH272	Bulbus lilii	Chuan Bai He	å·ç™¾åˆ
TCMH212	Iphigenia indica	Cao Bei Mu	è‰è´æ¯
TCMH2335	Hemerocallis fulva	Xuan Cao Gen	è±è‰æ ¹

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC931	C22H25NO6	Colchicine	399.17	-0.4721	3.11	1.463	4	1	86.58	11	3	29
TCMC1612	C22H25NO6	N-(1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl)Acetamide	399.17	-0.4721	3.11	1.463	4	1	86.58	11	3	29
TCMC2264	C13H8O4	1,7-Dihydroxyxanthone	228.04	-1.3385	2.45	1.577	1	2	66.76	2	3	17
TCMC2517	C14H10O4	2-Hydroxy-1-Methoxyxanthone	242.06	-0.93	2.56	2.307	1	1	55.76	3	3	18

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Iphigenia indica è‰è´æ¯

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC931

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2517

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2264

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1612

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Iphigenia indica è‰è´æ¯