Description of the Component
Component ID |
TCMH1906 |
Latin Name |
Cimicifuga foetida |
English Name |
Bugbane |
Chinese Pinyin Name |
Sheng Ma |
中文名 |
å‡éº» |
TCM Properties |
Minor cold,Pungent |
TCM Meridians |
Lung,Spleen,Large Intestine,Stomach |
Therapeutic Class English |
For relieving exterior syndrome |
Therapeutic Class Chinese |
解表 |
Functions |
induce perspiration and promote eruption, remove toxic heat, and cure drooping and ptosis |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
Sichuan Province,Chongqing, Heilongjiang Province |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
|
Barcode Source |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMF7260 | 益气èªæ˜Žæ±¤ | |
| TCMF2434 | Added Flavor DFZ Heat Clearing Decoction | åŠ å‘³åœ°è‚¤å汤 |
| TCMF2390 | Added Flavor Interior Tonification Decoction | åŠ å‘³è¡¥ä¸ç›Šæ°”汤 |
| TCMF1313 | Bolus for Reinforcing Middle-jiao and Replenishing Qi | è¡¥ä¸ç›Šæ°”丸 |
| TCMF2021 | Bolus for Reinforcing Middle-jiao and Replenishing Qi | è¡¥ä¸ç›Šæ°”丸 |
| TCMF3899 | Bu Qi Yi Qi Tablets | 补气益气片 |
| TCMF609 | Bu Zhong Yi Qi Granules | è¡¥ä¸ç›Šæ°”颗粒 |
| TCMF3108 | Bu Zhong Yi Qi Ointment | è¡¥ä¸ç›Šæ°”è† |
| TCMF3125 | Bu Zhong Yi Qi Pills | è¡¥ä¸ç›Šæ°”丸 |
| TCMF3116 | Bu Zhong Yi Qi Recipe | è¡¥ä¸ç›Šæ°”åˆå‰‚ |
| TCMF608 | Bu Zhong Yi Qi Recipe | è¡¥ä¸ç›Šæ°”åˆå‰‚ |
| TCMFx3251 | Chi Tong Ning | é½¿ç—›å® |
| TCMF3513 | Chuang Yang Ointment | ç–®ç–¡è† |
| TCMFx3562 | Chun Chi Qing Wei Pills | 唇齿清胃丸 |
| TCMF2697 | Cimicifuga and Kudzu Decoction | å‡éº»è‘›æ ¹æ±¤ |
| TCMF2716 | Cimicifuga Formula | ä¹™å—汤 |
| TCMF7371 | Dang Gui Nian Tong Decoction | 当归拈痛汤 |
| TCMF503 | Dang Gui Nian Tong Pills | 当归拈痛丸 |
| TCMF3078 | Dang Gui Nian Tong Pills | 当归拈痛丸 |
| TCMF3070 | Dang Gui Nian Tong Recipe | 当归拈痛åˆå‰‚ |
| TCMF2073 | Danger Relieving Decoction | |
| TCMF2052 | Decoction for Dysphagia | 通幽汤 |
| TCMF2333 | Decoction for Lifting Up Yang and Expelling Fire | 生阳散ç«æ±¤ |
| TCMF1723 | Decoction for Raising Primordial Energy | 举元煎 |
| TCMF2609 | Decoction for Restoring Yin and Purging Fire | |
| TCMF2204 | Decoction for Strenthening Middle Jiao and Benefiting Vital Energy | è¡¥ä¸ç›Šæ°”汤 |
| TCMF7252 | Decoction for Strenthening Middle Jiao and Benefiting Vital Energy | è¡¥ä¸ç›Šæ°”汤 |
| TCMF2559 | Decoction of Angelicae Sinensis for Analgesic | 当归拈痛汤 |
| TCMFx1669 | Decoction of Cimicifugae and Astragali seu Hedysari | å‡éº»é»„芩汤 |
| TCMF1668 | Decoction of Cimicifugae and Puerariae | å‡éº»è‘›æ ¹æ±¤ |
| TCMF1991 | Early Stage Decoction | |
| TCMF3893 | Er Tong Hui Chun Granules | 儿童回春颗粒 |
| TCMF3901 | Er Tong Hui Chun Pills | 儿童回春丸 |
| TCMFx3079 | Er Xian Pills | 二仙丸 |
| TCMF6996 | Fu Fang Jue Ming Tablets | å¤æ–¹å†³æ˜Žç‰‡ |
| TCMFx6922 | Fu Kang Oral Liquid | 妇康å£æœæ¶² |
| TCMF3705 | Gan Mao Jie Biao Pills | 感冒解表丸 |
| TCMF3280 | Gong Xue Ting Granules | 宫血åœé¢—ç²’ |
| TCMFx478 | Gua Shuang Tui Re Ling Capsule | 瓜霜退çƒçµèƒ¶å›Š |
| TCMFx3654 | Gua Shuang Tui Re Ling Capsules | 瓜霜退çƒçµèƒ¶å›Š |
| TCMF2350 | Hepatitis B Decoction | 益è‚汤 |
| TCMF4066 | Huang Lian Qing Wei Pills | 黄连清胃丸 |
| TCMFx2852 | Ji Chuan Decoction | 济å·ç…Ž |
| TCMFx1803 | Jichuan Decoction | 济å·ç…Ž |
| TCMF648 | Jin Hua Ming Mu Pills | 金花明目丸 |
| TCMF2469 | Kidney Tonification Decoction | |
| TCMF2661 | Kudzu Decoction | è‘›æ ¹æ±¤ |
| TCMF2889 | Liang Xue Di Huang Decoction | 凉血地黄汤 |
| TCMF4179 | Liang Xue Qu Feng Syrup | 凉血祛风糖浆 |
| TCMF1840 | Lifting and Benefiting Decoction | |
| TCMFx4965 | Lv Xue | 绿雪 |
| TCMFx4973 | Lv Xue Capsules | 绿雪胶囊 |
| TCMF2650 | Magnolia Flower Clear the Lung Decoction | 辛夷清肺汤 |
| TCMF2462 | Plus and Minus Eight Pearl Decoction | åŠ å‡å…«ç汤 |
| TCMF2182 | Plus and Minus Qi Benefiting Decoction | åŠ å‡ç›Šæ°”固冲汤 |
| TCMF4722 | Pu Ji Hui Chun Pills | 普济回春丸 |
| TCMF7392 | Pu Ji Xiao Du Decoction | 普济消毒饮 |
| TCMFx2535 | Purple Snowy Powder | 紫雪丹 |
| TCMF4848 | Qi Li De Kang Tablets | 芪力得康片 |
| TCMF2109 | Qi Lifting Decoction | |
| TCMF2318 | Qin Jiu Turtle Shell Decoction | 秦艽鳖甲饮 |
| TCMF7305 | Qing Shu Yi Qi Decoction | 清暑益气汤 |
| TCMF73 | Qing Shu Yi Qi Pills | 清暑益气丸 |
| TCMF5738 | Qing Shu Yi Qi Pills | 清暑益气丸 |
| TCMFx2835 | Qing Wei Powder | 清胃散 |
| TCMFx7323 | Qing Wei Powder | 清胃散 |
| TCMFx5006 | Qing Yu Bi Wen Dan | 庆余辟瘟丹 |
| TCMFx490 | Qing Yu Pi Wen Dan | 庆余辟瘟丹 |
| TCMF5689 | Ru Lu Ointment | ä¹³é¹¿è† |
| TCMF7339 | San Zhong Kui Jian Decoction | 散肿溃åšæ±¤ |
| TCMF1963 | SG Two Worm Decoction | |
| TCMFx5703 | Shang Ke Zhuang Gu Ointment | ä¼¤ç§‘å£®éª¨è† |
| TCMFx5366 | Shen Nong Zhen Tong Ointment | ç¥žå†œé•‡ç—›è† |
| TCMF7346 | Sheng Ma Ge Gen Decoction | å‡éº»è‘›æ ¹æ±¤ |
| TCMFx2862 | Sheng Xian Decoction | å‡é™·æ±¤ |
| TCMF7345 | Shi Shen Decoction | å神汤 |
| TCMFx1728 | Stomach Cooling Powder | 清胃散 |
| TCMF2684 | Tonify the Middle and Augment the Qi Decoction | è¡¥ä¸ç›Šæ°”汤 |
| TCMF5156 | Tou Biao Hui Chun Pills | é€è¡¨å›žæ˜¥ä¸¸ |
| TCMF2501 | Tree Flower Haemorrhoid Control Decoction | æ§èŠ±æ¶ˆç—”汤 |
| TCMF953 | Xiao Cuo Pills | 消痤丸 |
| TCMF6006 | Xiao Cuo Pills | 消痤丸 |
| TCMF6584 | Xiao Er Bi Yan Tablets | å°å„¿é¼»ç‚Žç‰‡ |
| TCMFx6005 | Xiao Er Jing An Pills | å°å„¿æƒŠå®‰ä¸¸ |
| TCMF2825 | Xin Yi Powder | 辛夷散 |
| TCMF7347 | Xin Yi Powder | 辛夷散 |
| TCMF7331 | Xin Yi Qing Fei Decoction | 辛夷清肺汤 |
| TCMF6575 | Xue Ya Ping Tablets | 血压平片 |
| TCMF6598 | Xun Ma Zhen Pills | è¨éº»ç–¹ä¸¸ |
| TCMF6566 | Yi Qi Cong Ming Pills | 益气èªæ˜Žä¸¸ |
| TCMF7398 | Yi Zi Decoction | ä¹™å—汤 |
| TCMF1129 | Zhang Yan Ming Tablet | 障眼明片 |
| TCMF6040 | Zhang Yan Ming Tablets | 障眼明片 |
| TCMFx6833 | Zhang Zhou Shen Qu | 漳州神曲 |
| TCMF6437 | Zhi Hong Chang Bi Pills | æ¢çº¢è‚ 辟丸 |
| TCMF315 | Zhi Hong Chang Pi Pills | æ¢çº¢è‚ 辟丸 |
| TCMFx120 | Zi Xue Powder | 紫雪散 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
| TCMT150 | RORC | Nuclear receptor ROR-gamma | Nuclear receptor | P51449 |
| TCMT159 | TYR | Tyrosinase | Oxidoreductase | P14679 |
| TCMT160 | HTR7 | Serotonin 7 (5-HT7) receptor | GPCR | P34969 |
| TCMT161 | HCAR2 | Hydroxycarboxylic acid receptor 2 | GPCR | Q8TDS4 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT164 | PTGS1 | Cyclooxygenase-1 | Oxidoreductase | P23219 |
| TCMT166 | AKR1C2 | Aldo-keto reductase family 1 member C2 | Oxidoreductase | P52895 |
| TCMT167 | AKR1C3 | Aldo-keto-reductase family 1 member C3 | Oxidoreductase | P42330 |
| TCMT168 | AKR1C4 | Aldo-keto reductase family 1 member C4 | Oxidoreductase | P17516 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT189 | DUSP3 | Dual specificity protein phosphatase 3 | Hydrolase | P51452 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT221 | ABCB11 | Bile salt export pump | Transporter | O95342 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
| TCMT280 | AKR1B10 | Aldo-keto reductase family 1 member B10 | Oxidoreductase | O60218 |
| TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
| TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
| TCMT320 | MMP3 | Matrix metalloproteinase 3 | Hydrolase | P08254 |
| TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT45 | APP | Beta amyloid A4 protein | Unclassified | P05067 |
| TCMT6 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | Transcription factor | P19838 |
| TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT95 | MPG | DNA-3-methyladenine glycosylase | Hydrolase | P29372 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1108 | Integrase |
| TCMT1218 | Staphylococcus aureus |
| TCMT1251 | Candida albicans |
Ingredient Structrues
Ingredient ID: TCMC847
Formula: C9H8O4
Ingredient ID: TCMC7330
Formula: C37H58O10
Ingredient ID: TCMC6687
Formula: C37H58O11
Ingredient ID: TCMC6462
Formula: C22H26N2O4
Ingredient ID: TCMC6415
Formula: C35H56O9
Ingredient ID: TCMC6307
Formula: C30H48O5
Ingredient ID: TCMC630
Formula: C37H56O11
Ingredient ID: TCMC6298
Formula: C22H28O10
Ingredient ID: TCMC4053
Formula: C12H8O4
Ingredient ID: TCMC3966
Formula: C29H50O
Ingredient ID: TCMC3865
Formula: C16H18O6
Ingredient ID: TCMC2906
Formula: C13H10O4
Ingredient ID: TCMC2084
Formula: C11H12O5
Ingredient ID: TCMC2037
Formula: C7H6O3
Ingredient ID: TCMC1390
Formula: C10H10O4
Ingredient ID: TCMC1173
Formula: C10H10O4
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC630 | C37H56O11 | Actein | 676.38 | -0.9166 | 4.32 | 5.056 | 11 | 4 | 156.67 | 15 | 9 | 48 | 2 |
| TCMC847 | C9H8O4 | Caffeic Acid | 180.04 | -0.7993 | 2.01 | 1.141 | 2 | 3 | 77.76 | 5 | 1 | 13 | 0 |
| TCMC1173 | C10H10O4 | Ferulic Acid | 194.06 | -0.3908 | 2.12 | 1.231 | 2 | 2 | 66.76 | 6 | 1 | 14 | 0 |
| TCMC1390 | C10H10O4 | Isoferulic Acid | 194.06 | -0.3908 | 2.12 | 1.231 | 2 | 2 | 66.76 | 6 | 1 | 14 | 0 |
| TCMC2037 | C7H6O3 | Salicylic Acid | 138.03 | -0.7001 | 1.9 | 2.264 | 2 | 2 | 57.53 | 3 | 1 | 10 | 0 |
| TCMC2084 | C11H12O5 | Sinapinate | 224.07 | -0.4426 | 2.12 | 0.787 | 2 | 2 | 75.99 | 8 | 1 | 16 | 0 |
| TCMC2906 | C13H10O4 | Visnagin | 230.0579088 | -0.3326 | 2.45 | 1.097 | 1 | 0 | 39.44 | 1 | 3 | 17 | 0 |
| TCMC3865 | C16H18O6 | Cimifugin | 306.1103383 | -0.8588 | 2.56 | 0.019 | 3 | 2 | 75.99 | 3 | 3 | 22 | 0 |
| TCMC3966 | C29H50O | Sitosterol,Î’-Sitosterol | 414.3861662 | 1.3 | 4.54 | 11.595 | 1 | 1 | 20.23 | 6 | 4 | 30 | 1 |
| TCMC4053 | C12H8O4 | Norvisnagin | 216.0422587 | -0.7411 | 2.34 | 0.578 | 1 | 1 | 50.44 | 0 | 3 | 16 | 0 |
| TCMC6298 | C22H28O10 | Visamminol | 452.1682471 | -1.9337 | 2.78 | -0.052 | 7 | 4 | 134.91 | 5 | 4 | 32 | 0 |
| TCMC6307 | C30H48O5 | Cimigenol | 488.3501746 | 0.4019 | 4.21 | 6.252 | 5 | 3 | 79.15 | 1 | 7 | 35 | 1 |
| TCMC6415 | C35H56O9 | Cimiaceroside B | 620.3924334 | -1.0275 | 4.32 | 6.027 | 9 | 5 | 138.07 | 2 | 8 | 44 | 1 |
| TCMC6462 | C22H26N2O4 | Cimicilen | 383.1970823 | -3.4516 | 3.22 | 2.071 | 4 | 2 | 71.28 | 2 | 6 | 28 | 0 |
| TCMC6687 | C37H58O11 | 12Î’-Acetoxycimigenol-3-O-Î’-D-Xylopyranoside | 678.3979127 | -1.0283 | 4.32 | 4.253 | 11 | 5 | 164.37 | 5 | 8 | 48 | 1 |
| TCMC7330 | C37H58O10 | 23-O-Acetylshengmanol 3-O-Α-L-Arabinopyranoside | 662.4029981 | -0.802 | 4.43 | 5.969 | 10 | 4 | 155.28 | 8 | 7 | 47 | 1 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
