Prescription Description
| Prescription ID | TCMFx5798 |
| Pinyin Name | Run Ji Pi Fu Gao |
| Chinese Name | æ¶¦è‚Œçš®è‚¤è† |
| English Name | Run Ji Pi Fu Ointment |
| Function Description | 粉刺, 酒糟鼻, 雀斑, 白驳风, 脚癣 |
| Indications | Psoriasis, Dermatophytosis |
| Disease ICD-11 Category |
EA90 [Psoriasis, 银屑病
]; 1F28 [Dermatophytosis, 足癣 ]; |
| Human Tissues Associated with Indication | Skin |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH354 | Hydnocarpus anthelminticus | 大风å | TCMH354 | |
| TCMH823 | Semen juglandis | æ ¸æ¡ƒä» | TCMH823 | |
| TCMH168 | Ricinus communis | 蓖麻å | TCMH168 | ITSAB3015-14 |
| TCMH582 | Cera flava | 蜂蜡 | TCMH582 | |
| TCMH1915 | NA | å‡è¯ | TCMH1915 | |
| TCMH2585 | Cinnamomum camphora | 樟脑 | TCMH2585 | SDH069-14 |
| TCMH2033 | Pinus massoniana | æ¾é¦™ | TCMH2033 | ITSAM2023-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT151 | PRKCA | Protein kinase C alpha | Kinase | P17252 |
| TCMT152 | PRKCB | Protein kinase C beta | Kinase | P05771 |
| TCMT153 | PRKCG | Protein kinase C gamma | Kinase | P05129 |
| TCMT154 | PRKCD | Protein kinase C delta | Kinase | Q05655 |
| TCMT155 | PRKCE | Protein kinase C epsilon | Kinase | Q02156 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT217 | CYP2C8 | Cytochrome P450 2C8 | Oxidoreductase | P10632 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT239 | PIM1 | Serine/threonine-protein kinase PIM1 | Kinase | P11309 |
| TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
| TCMT260 | FLT3 | Tyrosine-protein kinase receptor FLT3 | Kinase | P36888 |
| TCMT261 | DAPK1 | Death-associated protein kinase 1 | Kinase | P53355 |
| TCMT322 | MMP13 | Matrix metalloproteinase 13 | Hydrolase | P45452 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT369 | IGF1R | Insulin-like growth factor I receptor | Kinase | P08069 |
| TCMT370 | KDR | Vascular endothelial growth factor receptor 2 | Kinase | P35968 |
| TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
| TCMT388 | AXL | Tyrosine-protein kinase receptor UFO | Kinase | P30530 |
| TCMT401 | MET | Hepatocyte growth factor receptor | Kinase | P08581 |
| TCMT422 | CAMK2B | CaM kinase II beta | Kinase | Q13554 |
| TCMT445 | NEK2 | Serine/threonine-protein kinase NEK2 | Kinase | P51955 |
| TCMT462 | NEK6 | Serine/threonine-protein kinase NEK6 | Kinase | Q9HC98 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
| TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
| TCMT784 | AVPR2 | Vasopressin V2 receptor | GPCR | P30518 |
| TCMT785 | CXCR1 | Interleukin-8 receptor A | GPCR | P25024 |
| TCMT786 | CCR4 | C-C chemokine receptor type 4 | GPCR | P51679 |
| TCMT791 | PKN1 | Protein kinase N1 | Kinase | Q16512 |
| TCMT793 | PYGL | Liver glycogen phosphorylase | Transferase | P06737 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1172 | Staphylococcus aureus subsp. aureus RN4220 |
| TCMT1174 | Mycobacterium bovis BCG |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1184 | Mycobacterium fortuitum |
| TCMT1185 | Mycobacterium phlei |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1193 | Staphylococcus |
| TCMT1195 | Streptococcus pasteurianus |
| TCMT1196 | Salmonella |
| TCMT1197 | Shigella sp. |
| TCMT1198 | Serratia marcescens |
| TCMT1200 | Bacillus thuringiensis |
| TCMT1208 | Escherichia coli K12 |
| TCMT1212 | Verticillium dahliae |
| TCMT1213 | Neisseria gonorrhoeae |
| TCMT1214 | Enterococcus faecium |
| TCMT1216 | Vibrio cholerae |
| TCMT1217 | Bacillus anthracis |
| TCMT1218 | Staphylococcus aureus |
| TCMT1222 | Plasmodium falciparum D6 |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1224 | Proteus mirabilis |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1227 | Streptococcus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1231 | Human herpesvirus 1 strain KOS |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1236 | Mycobacterium bovis |
| TCMT1239 | Mycobacterium marinum |
| TCMT1243 | Aspergillus flavus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1255 | Human immunodeficiency virus 1 |
| TCMT1262 | Mycoplasma putrefaciens |
| TCMT1266 | Mycobacterium abscessus |
| TCMT1267 | Mycobacterium chelonae |
| TCMT1268 | Nocardia farcinica |
| TCMT1269 | Mycobacterium ulcerans |
| TCMT1270 | Streptomyces coelicolor |
| TCMT1271 | Shigella flexneri |
| TCMT1273 | Pseudomonas putida |
| TCMT1275 | Erwinia chrysanthemi |
| TCMT1278 | Pseudomonas |
| TCMT1279 | Staphylococcus aureus subsp. aureus |
| TCMT1280 | Salmonella sp. |
| TCMT1286 | Bacillus cereus |
| TCMT1287 | Bacillus subtilis subsp. spizizenii ATCC 6633 |
| TCMT1289 | Shigella dysenteriae |
| TCMT1294 | Human parainfluenza virus 3 |
| TCMT1303 | Bacillus |
| TCMT1305 | Salmonella enteritidis |
| TCMT1311 | Pseudomonas tolaasii |
| TCMT1325 | Mycobacterium gordonae |
| TCMT1326 | Shigella |
| TCMT1328 | Enterococcus avium |
| TCMT1329 | Bacillus fortis |
| TCMT1330 | Salmonella enterica subsp. enterica serovar Paratyphi B |
| TCMT1331 | Acinetobacter sp. |
| TCMT1346 | Helicobacter pylori |
| TCMT1349 | Helicobacter pylori SS1 |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1390 | Human herpesvirus 2 strain G |
| TCMT1410 | Listeria monocytogenes |
| TCMT1412 | Salmonella typhimurium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1443 | Leishmania amazonensis |
| TCMT1444 | Fusarium oxysporum |
| TCMT1448 | Enterobacter aerogenes |
| TCMT1454 | Bacillus subtilis |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1460 | Mycobacterium intracellulare |
| TCMT1461 | Salmonella enterica subsp. enterica serovar Gallinarum |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples