Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2025	TCMT61	Induced myeloid leukemia cell differentiation protein Mcl-1	Homo sapiens	IC50: 2025.72 (nM), Ref:
TCMC1506	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 101.2 (nM), Ref: 26498393
TCMC1506	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 268.3 (nM), Ref: 26498393
TCMC1506	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 4.8 (nM), Ref: 26498393
TCMC2025	TCMT295	Matrix metalloproteinase-1	Homo sapiens	IC50: 5600 (nM), Ref: 23353736
TCMC2025	TCMT359	Tyrosine-protein kinase FYN	Homo sapiens	IC50: 1300 (nM), Ref: 17315853 IC50: 3600 (nM), Ref: 17315853 Ki: 7500 (nM), Ref: 17315853
TCMC1730	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 990 (nM), Ref: 18318466
TCMC1730	TCMT563	Dual specificity phosphatase Cdc25B	Homo sapiens	IC50: 2760 (nM), Ref: 19028102
TCMC1730	TCMT186	Monoamine oxidase B	Homo sapiens	Ki: 1500 (nM), Ref: 22071524
TCMC1730	TCMT208	Monoamine oxidase A	Homo sapiens	Ki: 7700 (nM), Ref: 22071524
TCMC1830	TCMT297	Fatty acid binding protein adipocyte	Homo sapiens	IC50: 930 (nM), Ref: 15357969
TCMC1830	TCMT298	Fatty acid binding protein muscle	Homo sapiens	IC50: 2600 (nM), Ref: 15357969
TCMC1830	TCMT808	Fatty acid binding protein epidermal	Homo sapiens	IC50: 1200 (nM), Ref: 15357969
TCMC1830	TCMT809	Fatty acid binding protein intestinal	Homo sapiens	IC50: 1700 (nM), Ref: 15357969
TCMC1830	TCMT810	Toll-like receptor 2	Homo sapiens	IC50: 5000 (nM), Ref: 16509590
TCMC1830	TCMT64	Peroxisome proliferator-activated receptor delta	Homo sapiens	IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC192	TCMT176	Acyl coenzyme A:cholesterol acyltransferase 1	Homo sapiens	IC50: 600 (nM), Ref: 17157006
TCMC192	TCMT263	Acyl coenzyme A:cholesterol acyltransferase 2	Homo sapiens	IC50: 800 (nM), Ref: 17157006

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2366	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 2.8 (ug/ml), Ref: 17845001
TCMC2385	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 12502328 MIC: 50 (ug/ml), Ref: 12502328
TCMC2385	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 50 (ug/ml), Ref: 12502328
TCMC2385	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC2388	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2388	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2388	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1730	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 1 (ug/ml), Ref: 17888665
TCMC2547	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 6.25 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2547	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC2547	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1830	TCMT1361	Neisseria meningitidis	Neisseria meningitidis	MIC: 50 (ug/ml), Ref: 19884363
TCMC1830	TCMT1382	Plasmodium falciparum (isolate K1 / Thailand)	Plasmodium falciparum K1	IC50: 3.8 (ug/ml), Ref: 20855214 IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830	TCMT1442	Leishmania donovani	Leishmania donovani	IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2552	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC2552	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 1.56 (ug/ml), Ref: 12502328
TCMC2552	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 1.56 (ug/ml), Ref: 12502328 MIC: 0.78 (ug/ml), Ref: 12502328
TCMC915	TCMT1246	Escherichia coli	Escherichia coli	MIC: 1 (ug/ml), Ref: 25791674
TCMC915	TCMT1454	Bacillus subtilis	Bacillus subtilis	MIC: 0.5 (ug/ml), Ref: 25791674
TCMC915	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 0.25 (ug/ml), Ref: 25791674
TCMC2069	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 12502328 MIC: 50 (ug/ml), Ref: 12502328
TCMC2069	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 50 (ug/ml), Ref: 12502328
TCMC2069	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 6.25 (ug/ml), Ref: 12502328
TCMC2613	TCMT1255	Human immunodeficiency virus 1	Human immunodeficiency virus 1	IC50: 15 (ug/ml), Ref: 9748372
TCMC2025	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC2025	TCMT1223	Staphylococcus epidermidis	Staphylococcus epidermidis	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC2025	TCMT1232	Pseudomonas aeruginosa	Pseudomonas aeruginosa	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC1578	TCMT1408	Colletotrichum gloeosporioides	Colletotrichum gloeosporioides	IC50: 0.09 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC1578	TCMT1245	Phytophthora cactorum	Phytophthora cactorum	IC50: 0.052 (ug/ml), Ref: 10.1016/j.cropro.2009.12.007
TCMC2025	TCMT1246	Escherichia coli	Escherichia coli	MBC: 0.12 (ug/ml), Ref: 18004816
TCMC624	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 6.25 (ug/ml), Ref: 12502328 MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC624	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 6.25 (ug/ml), Ref: 12502328
TCMC624	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 1.56 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328
TCMC2706	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 6.25 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328 MBC: 3.13 (ug/ml), Ref: 12502328
TCMC2706	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2706	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328 MBC: 1.56 (ug/ml), Ref: 12502328
TCMC2718	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718	TCMT1214	Enterococcus faecium	Enterococcus faecium	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 3.13 (ug/ml), Ref: 12502328 MIC: 3.13 (ug/ml), Ref: 12502328 MBC: 1.56 (ug/ml), Ref: 12502328 MIC: 1.56 (ug/ml), Ref: 12502328
TCMC2727	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 50 (ug/ml), Ref: 21115251 MBC: 50 (ug/ml), Ref: 18198837
TCMC2728	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 25 (ug/ml), Ref: 21115251 MBC: 100 (ug/ml), Ref: 15214779
TCMC2729	TCMT1214	Enterococcus faecium	Enterococcus faecium	MIC: 3.13 (ug/ml), Ref: 21115251 MBC: 6.25 (ug/ml), Ref: 15214779
TCMC2729	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 3.13 (ug/ml), Ref: 22364815 MIC: 3.13 (ug/ml), Ref: 19464173 MBC: 1.56 (ug/ml), Ref: 16180824 MIC: 1.56 (ug/ml), Ref: 12502331
TCMC2727	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 50 (ug/ml), Ref: 22435669 MIC: 50 (ug/ml), Ref: 18183025 MIC: 50 (ug/ml), Ref: 12828488 MBC: 100 (ug/ml), Ref: 18809939
TCMC2729	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 3.13 (ug/ml), Ref: 17521907 MIC: 3.13 (ug/ml), Ref: 18989978 MBC: 6.25 (ug/ml), Ref: 21807513 MBC: 6.25 (ug/ml), Ref: 19752280
TCMC2728	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 100 (ug/ml), Ref: 17521907 MBC: 100 (ug/ml), Ref: 16570920 MIC: 25 (ug/ml), Ref: 18989978
TCMC2728	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MBC: 100 (ug/ml), Ref: 18598080 MIC: 50 (ug/ml), Ref: 17850214 MIC: 50 (ug/ml), Ref: 15497935
TCMC2727	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 100 (ug/ml), Ref: 21495717 MIC: 50 (ug/ml), Ref: 18989978 MBC: 50 (ug/ml), Ref: 26110443